home
***
CD-ROM
|
disk
|
FTP
|
other
***
search
/
Shareware Overload Trio 2
/
Shareware Overload Trio Volume 2 (Chestnut CD-ROM).ISO
/
dir26
/
med9410n.zip
/
M94A2468.TXT
< prev
next >
Wrap
Text File
|
1994-10-25
|
3KB
|
43 lines
Document 2468
DOCN M94A2468
TI Risk factors for male-to-female HIV transmission.
DT 9412
AU Guimaraes M; Castilho E; Cavalcante S; Lima LA; Gomes VR; UFMG, Brazil.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):297 (abstract no. PC0115). Unique
Identifier : AIDSLINE ICA10/94370107
AB OBJECTIVE: To determine factors associated with male-to-female HIV
transmission in Rio, Brazil. METHODS: HIV positive male index cases (IC)
and their female partners (FP) were recruited from participant centers
in Rio de Janeiro. They should be sexually active within the past year
and female partners should not have other risk factor for HIV. Couples
were interviewed for risk factors and had blood collected for HIV, HBV,
syphilis, T4/T8 count exams. Analysis included: chi-square, t-test, Odds
Ratio (OR) with 95% confidence limits and logistic regression modeling.
RESULTS: As of Dec 1993, 340 couples were available for analysis and 48%
of the women were HIV-1 positive. Most ICs were bisexuals (44%), had
AIDS (51%), were in long term relationships (78% for 24+ months) but
only recently informed the FPs of their HIV status (66% within 6 months
prior to the interview). Most women were 30+ years old (65%), had more
than 8 years of education (51%), had monthly family income > or = US$250
(54%) and had only the IC as sexual partner in the past year (78%).
Logistic regression modeling showed the following factors to be
independently associated with HIV-1: anal sex (OR = 2.58, CI =
1.49-4.46); lack of vaginal condom use (OR = 2.38, CI = 1.17-4.85); IC
clinical stage (OR = 1.87, CI = 1.14-3.06); frequency of contacts (OR =
2.07, CI = 1.26-3.39) and age began regular sexual life (< 19 y.o.) (OR
= 1.62, CI = .99-2.68), though borderline significant. CONCLUSIONS: 1.
The high prevalence of HIV-1 in this population (48%) can be explained
by the high frequency, unprotected vaginal sex and anal sex, with index
cases at advanced stage of HIV infection; 2. Although STDs
(history/markers) are important cofactors among heterosexual
transmission of HIV in Africa, in this population their independent
effect could not be demonstrated; 3. Rather, heterosexual transmission
in Rio de Janeiro is more similar to USA and Europe partner studies.
DE Adult Condoms Female Human HIV Infections/*TRANSMISSION *HIV-1
Male Risk Factors *Sex Behavior Support, Non-U.S. Gov't Support,
U.S. Gov't, P.H.S. MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).